ALCL, ALK-positive Clinical Trials

ALK-positive anaplastic large cell lymphoma (ALCL) is a CD30-expressing T-cell lymphoma that typically responds well to chemotherapy and brentuximab-based regimens. Below are 80 curated trials in our database for ALK-positive ALCL patients.

80

Total matches

8

Highest priority

66

Recruiting now

21

With US sites

9

Phase 3 trials

Showing 80 curated ALCL, ALK+ trials

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Highest Priority — Landmark & Practice-Changing (8)

Phase 3 randomized trials with strong rationale.

Phase 3RecruitingPriority 1 · Highest priorityNCT07300514

Golidocitinib Versus Placebo as Maintenance Therapy for Peripheral T-Cell Lymphoma

This Phase 3 trial is comparing different first-line treatment approaches for people newly diagnosed with a type of T-cell lymphoma called AITL. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Fudan University

Treatment length

Ask the trial team for details

Phase 3RecruitingPriority 1 · Highest priorityNCT06561048

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

This Phase 3 trial is comparing Soquelitinib, Belinostat, and other medications against other options for people whose a type of T-cell lymphoma called AITL has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is widely available at 21 US locations.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

21 US sites · California, Connecticut, Florida +14

Sponsor

Corvus Pharmaceuticals, Inc.

Treatment length

Ask the trial team for details

Phase 3RecruitingPriority 1 · Highest priorityNCT06776952

A Randomized, Double-blind, Multicenter Phase III Study of XNW5004 Tablets in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma

This Phase 3 trial is comparing XNW5004 ; Chidamide placebo and XNW5004 placebo; Chidamide against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Days to 70 Days years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Evopoint Biosciences Inc.

Treatment length

Ask the trial team for details

Phase 3RecruitingPriority 1 · Highest priorityNCT05931263

A Randomized Clinical Trial Comparing Chi-BEAM With BEAM Regimen Combined With ASCT for the Treatment of ND PTCL

This Phase 3 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 65 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

The First Affiliated Hospital with Nanjing Medical University

Treatment length

Ask the trial team for details

Phase 3RecruitingPriority 1 · Highest priorityNCT07234162

A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19)

This Phase 3 trial is comparing Golidocitinib, Chidamide, and other medications against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Dizal Pharmaceuticals

Treatment length

Ask the trial team for details

Phase 3RecruitingPriority 1 · Highest priorityNCT06072131

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

This Phase 3 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 11 US locations across multiple states.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

11 US sites · California, Colorado, Florida +4

Sponsor

Acrotech Biopharma Inc.

Treatment length

Ask the trial team for details

Phase 3RecruitingPriority 1 · Highest priorityNCT07414758

Golidocitinib Versus Placebo as Maintenance Therapy in PTCL Patients With Response (CR/PR) After First-Line Chemotherapy

This Phase 3 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Treatment length

Ask the trial team for details

Phase 3RecruitingPriority 1 · Highest priorityNCT06947967

Tucidinostat in Combination With CHOP in Newly Diagnosed Peripheral T-Cell Lymphoma With Follicular Helper of T Cell Phenotype

This Phase 3 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 80 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Chipscreen Biosciences, Ltd.

Treatment length

Ask the trial team for details

High Priority — Strong Clinical Rationale (17)

Important trials worth strongly considering.

Phase 1, Phase 2RecruitingPriority 2 · High priorityNCT06137144

AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

This Phase 1, Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with a type of T-cell lymphoma called AITL. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 7 US locations across multiple states.

Who it's for

  • Age 12 Years or older
  • Newly diagnosed, not yet treated

Location

7 US sites · California, Florida, Georgia +4

Sponsor

AstraZeneca

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 2 · High priorityNCT05313243

Pembrolizumab and Brentuximab Vedotin in Subjects With Relapsed/Refractory T-cell Lymphoma

This Phase 2 trial is testing Brentuximab vedotin and Pembrolizumab for people whose anaplastic large cell lymphoma (ALCL) has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. It is available at 2 US locations.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

2 US sites · Connecticut, Massachusetts

Sponsor

Yale University

Treatment length

Ask the trial team for details

Phase 2Not yet recruitingPriority 2 · High priorityNCT07180771

A Study of Bosmolisib (BR101801) in Participants With R/R PTCL.

This Phase 2 trial is testing BR101801 for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 19 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Boryung Pharmaceutical Co., Ltd

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 2 · High priorityNCT05934513

A Study of GFH009 Monotherapy in Patients with Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

This Phase 1, Phase 2 trial is testing GFH009 for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Genfleet Therapeutics (Shanghai) Inc.

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 2 · High priorityNCT06909877

Study to Evaluate Efficacy and Safety of HH2853 in Relapsed/Refractory Peripheral T-cell Lymphoma

This Phase 1, Phase 2 trial is testing HH2853 Tablets for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Haihe Biopharma Co., Ltd.

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 2 · High priorityNCT05833724

Chidamide in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (R/R PTCL)

This Phase 2 trial is evaluating Chidamide as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 20 Years to 75 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Great Novel Therapeutics Biotech & Medicals Corporation

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 2 · High priorityNCT04747236

Randomized Phase IIB Trial of Oral Azacytidine Plus Romidepsin Versus Investigator's Choice in PTCL

This Phase 2 trial is comparing Azacytidine, Romidepsin, and other medications against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 6 US locations across multiple states.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

6 US sites · California, Connecticut, New York +3

Sponsor

University of Virginia

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 2 · High priorityNCT03922724

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

This Phase 2 trial is comparing ATL-RIC, mRIC, and other medications against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 2 US locations.

Who it's for

  • Age 12 Years to 120 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

2 US sites · Maryland, Minnesota

Sponsor

National Cancer Institute (NCI)

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 2 · High priorityNCT07523555

Adaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic Malignancies

This Phase 1, Phase 2 trial is comparing Autologous CD19/CD22 dual-target CAR-T module, Autologous CD19/CD20 dual-target CAR-T module, and other medications against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Beijing Biotech

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 2 · High priorityNCT07013565

Chemoimmunotherapy for ALK+ Relapsed/Refractory ALCL

This Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with ALK-positive ALCL. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 1 US location.

Who it's for

  • Age 1 Year to 39 Years years
  • Newly diagnosed, not yet treated

Location

1 US site · New York

Sponsor

New York Medical College

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 2 · High priorityNCT06630091

A Phase II, Single-center, Single-arm Study Evaluating the Safety and Efficacy of Golidocitinib in the Management of Newly Diagnosed Peripheral T Cell Lymphoma Patients (GOLDEN Study) and Correlative Study

This Phase 2 trial is evaluating Golidocitinib, Cyclophosphamide, and other medications as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. It is available at 1 US location.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

1 US site · Texas

Sponsor

M.D. Anderson Cancer Center

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 2 · High priorityNCT04068597

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

This Phase 1, Phase 2 trial is comparing CCS1477, Pomalidomide, and other medications against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 6 US locations across multiple states.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

6 US sites · Georgia, Indiana, Maryland +2

Sponsor

CellCentric Ltd.

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 2 · High priorityNCT05463263

A Phase 1/2 Study of STP938 (Dencatistat) for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas

This Phase 1, Phase 2 trial is comparing STP938 against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 3 US locations.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

3 US sites · Colorado, Florida, New York

Sponsor

Step Pharma, SAS

Treatment length

Ask the trial team for details

Phase 3RecruitingPriority 2 · High priorityNCT06122389

SHR2554 Clinical Study of Chidamide in the Treatment of T-cell Lymphoma

This Phase 3 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Jiangsu HengRui Medicine Co., Ltd.

Treatment length

Ask the trial team for details

Phase 2Not yet recruitingPriority 2 · High priorityNCT06702605

To Evaluate XNW5004 Tablets in Patients with Relapsed or Refractory Peripheral T Cell Lymphoma

This Phase 2 trial is testing XNW5004 tablets for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Evopoint Biosciences Inc.

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 2 · High priorityNCT06534060

MB-105 in Patients With CD5 Positive T-cell Lymphoma

This Phase 2 trial is testing Genetic: MB-105 for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. It is available at 12 US locations across multiple states.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

12 US sites · California, Colorado, Florida +8

Sponsor

March Biosciences Inc

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 2 · High priorityNCT04195633

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

This Phase 2 trial is comparing Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, and other medications against other options for people whose anaplastic large cell lymphoma (ALCL) has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 1 US location.

Who it's for

  • Age 6 Months or older
  • Lymphoma came back or did not respond to prior treatment

Location

1 US site · Washington

Sponsor

Fred Hutchinson Cancer Center

Treatment length

Ask the trial team for details

Moderate Priority — Worth Discussing With Your Team (33)

Reasonable options worth a conversation.

Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07535762

Aclarubicin Plus Cyclophosphamide, Vincristine, and Prednisone (CAOP) in Patients With Previously Untreated Peripheral T-Cell Lymphoma

This Phase 2 trial is evaluating Aclarubicin, Cyclophosphamide, and other medications as a treatment for people newly diagnosed with a type of T-cell lymphoma called AITL. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 65 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Shanghai Jiao Tong University School of Medicine

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT07372352

Zeprumetostat, Azacitidine Combined With Lipo-MIT in R/R PTCL

This Phase 2 trial is evaluating Zeprumetostat, Azacitidine (AZA), and other medications as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

The First Affiliated Hospital of Soochow University

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT05963347

Go-CHOP as the Frontline Therapy for PTCL

This Phase 2 trial is evaluating Golidocitinib and CHOP Regimen as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Henan Cancer Hospital

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT05675813

Genotype-guided Treatment in Newly Diagnosed PTCL

This Phase 1, Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Ruijin Hospital

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT04512534

Sintilimab Combined With Chidamide in Treating Peripheral T Cell Lymphoma

This Phase 2 trial is testing PD-1 antibody+ HDAC inhibitor for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Fudan University

Treatment length

Ask the trial team for details

Phase 1, Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07288814

Mitoxantrone Hydrochloride Liposome and Enlonstobart Combination Treatment in Patients With Relapsed or Refractory Peripheral T Cell Lymphoma (PTCL)

This Phase 1, Phase 2 trial is evaluating Mitoxantrone Hydrochloride Liposome & Enlonstobart as a treatment for people newly diagnosed with T-cell lymphoma. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Sun Yat-Sen University Cancer Center

Treatment length

Ask the trial team for details

Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07032532

Assessing An Oral JAK1 Inhibitor, Golidocitinib, in Patients Who Have Newly Diagnosed Peripheral T-Cell Lymphoma (JACKPOT23)

This Phase 2 trial is evaluating Golidocitinib and Golidocitinib plus CHOP as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Sun Yat-sen University

Treatment length

Ask the trial team for details

Phase 1, Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07209163

Combination Therapy With Tazemetostat in Relapsed and Refractory Peripheral T-cell Lymphoma

This Phase 1, Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Ruijin Hospital

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT06855823

A Phase I/II Study of Golidocitinib Combined with Pomalidomide in R/R PTCL

This Phase 1, Phase 2 trial is testing Golicitinib combined with Pomadomide for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 80 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Sun Yat-sen University

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT06421948

Linperlisib Combined With Chidamide in Patients With PTCL

This Phase 1, Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 80 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Yanyan Liu

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT04922567

Efficacy and Safety of Lenalidomide Plus CHOP vs CHOP in Patients With Untreated Peripheral T-Cell Lymphoma

This Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT06739265

Golidocitinib Plus CHOP in Newly Diagnosed PTCL

This Phase 1, Phase 2 trial is evaluating Golidocitinib plus CHOP as a treatment for people newly diagnosed with T-cell lymphoma. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Peking Union Medical College Hospital

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT06160843

Pembrolizumab and Olaparib Treatment for Relapsed or Refractory Peripheral T-Cell Lymphoma

This Phase 2 trial is testing Pembrolizumab IV infusion Q3W and with daily oral Olaparib. for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 21 Years to 99 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

National Cancer Centre, Singapore

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT05976997

Prospective, Single Arm, Single Center Study of Duvelisib Combined With Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma (PTCL)

This Phase 2 trial is evaluating Duvelisib and Chidamide as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Liling Zhang

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT07018752

A Platform Trial Evaluating New Drugs or Combination in R/R Peripheral T-cell Lymphomas

This Phase 1, Phase 2 trial is comparing roginolisib, golcadomide, and other medications against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

The Lymphoma Academic Research Organisation

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT05949944

Linperlisib in Combination With CHOP in Previously Untreated Peripheral T-Cell Lymphoma

This Phase 1, Phase 2 trial is evaluating Linperlisib in combination with CHOP as a treatment for people newly diagnosed with T-cell lymphoma. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Sun Yat-sen University

Treatment length

Ask the trial team for details

Phase 2, Phase 3RecruitingPriority 3 · Moderate priorityNCT07389616

A Clinical Trial of Cidabenamine Plus Azacitidine to Prevent Post-Transplant Progression in High-Risk Peripheral T-Cell Lymphoma

This Phase 2, Phase 3 trial is testing Cidabenamine and Azacitidine for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Treatment length

Ask the trial team for details

Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07279584

Golidocitinib Combined With GemOx in RR PTCL

This Phase 2 trial is testing golidocitinib and GEMOX for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Ruijin Hospital

Treatment length

Ask the trial team for details

Phase 1, Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07139353

Linperlisib Combined With Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma

This Phase 1, Phase 2 trial is testing Linperlisib and Chidamide for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Sun Yat-sen University

Treatment length

Ask the trial team for details

Phase 1, Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT06757387

Chidamide Plus Golidocitinib in Relapsed/Refractory Peripheral T-Cell Lymphoma

This Phase 1, Phase 2 trial is comparing chidamide and golidocitinib against other options for people whose T-cell lymphoma has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 80 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Peking University Cancer Hospital & Institute

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT07093710

Golidocitinib Combined With Mitoxantrone Hydrochloride Liposome or Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma

This Phase 1, Phase 2 trial is testing Golidocitinib, Mitoxantrone Hydrochloride Liposome, and other medications for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Sun Yat-sen University

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT06433362

CMOEP in the Treatment of Untreated Peripheral T-cell Lymphoma

This Phase 2 trial is evaluating CMOEP as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Tianjin Medical University Cancer Institute and Hospital

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT06151106

Chidamide and Duvalisibon for the Treatment of Refractory/Relapsed Peripheral T-cell Lymphoma

This Phase 2 trial is evaluating Chidamide combined with Duvillisib as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

The First Affiliated Hospital of Xiamen University

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT04925609

Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors

This Phase 1, Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with ALK-positive ALCL. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 1 Year to 25 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Princess Maxima Center for Pediatric Oncology

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT06468267

RIC With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Relapsed or Refractory PTCL.

This Phase 2 trial is testing Thiotepa for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Xianmin Song, MD

Treatment length

Ask the trial team for details

Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07347288

SHR2554 as Maintenance Therapy in Patients With Peripheral T-cell Lymphoma

This Phase 2 trial is evaluating SHR2554 Tablets as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

The First Affiliated Hospital with Nanjing Medical University

Treatment length

Ask the trial team for details

Phase 1, Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07493330

Genotype-guided Targeted Agents Plus EZH2i for Primary Refractory PTCL

This Phase 1, Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Ruijin Hospital

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT06176027

Azacytidine Plus CAOLD Regimen in Relapsed/Refractory Peripheral T-Cell Lymphomas

This Phase 1, Phase 2 trial is testing Azacytidine plus CAOLD regimen for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Navy General Hospital, Beijing

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT06519526

Exploratory Clinical Study of SHR-0302 and SHR-2554 in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma

This Phase 2 trial is testing SHR-0302 and SHR-2554 for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Fudan University

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT05182957

Clinical Study on Anti-PD-1 Plus Lenalidomide and Azacitidine in Relapsed/Refractory Peripheral T-cell Lymphoma

This Phase 2 trial is evaluating Anti-PD-1 monoclonal antibody, Lenalidomide, and other medications as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

The First Affiliated Hospital of Soochow University

Treatment length

Ask the trial team for details

Phase 2RecruitingPriority 3 · Moderate priorityNCT05572983

Phase Ⅱ Study of Chidamide in Combination With CHOP in Previously Untreated Peripheral T-Cell Lymphoma With Follicular Helper of T Cell Phenotype

This Phase 2 trial is evaluating Chidamide combined with CHOP and Chidamide as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Sun Yat-sen University

Treatment length

Ask the trial team for details

Phase 2, Phase 3RecruitingPriority 3 · Moderate priorityNCT05770037

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

This Phase 2, Phase 3 trial is studying Alectinib for people with anaplastic large cell lymphoma (ALCL). Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Must be well enough for treatment (adequate performance status)
  • See full trial listing for complete eligibility

Location

No US sites currently

Sponsor

Cancer Research UK

Treatment length

Ask the trial team for details

Phase 1, Phase 2RecruitingPriority 3 · Moderate priorityNCT06420076

Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells

This Phase 1, Phase 2 trial is testing CD5/CD7 CAR-T for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 2 Years to 90 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Essen Biotech

Treatment length

Ask the trial team for details

Lower Priority — Early-Stage or Limited Access (22)

Early-stage trials or limited site availability.

RecruitingPriority 4 · Lower priorityNCT05978141

A Registry for People With T-cell Lymphoma

This trial is studying Optional Blood Sample and Nail Sample for people with a type of T-cell lymphoma called AITL. The study measures how well this treatment works and monitors for side effects. It is widely available at 26 US locations.

Who it's for

  • See full trial listing for complete eligibility

Location

26 US sites · California, Colorado, Connecticut +12

Sponsor

Memorial Sloan Kettering Cancer Center

Treatment length

Ask the trial team for details

NARecruitingPriority 4 · Lower priorityNCT05444712

Transplantation After Complete Response In Patients With T-cell Lymphoma

This NA trial is comparing different first-line treatment approaches for people newly diagnosed with a type of T-cell lymphoma called AITL. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Hospices Civils de Lyon

Treatment length

Ask the trial team for details

Phase 1RecruitingPriority 4 · Lower priorityNCT07055477

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

This Phase 1 trial is comparing Cyclophosphamide, Fludarabine, and other medications against other options for people whose a type of T-cell lymphoma called AITL has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 1 US location.

Who it's for

  • Age 18 Years to 120 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

1 US site · Maryland

Sponsor

National Cancer Institute (NCI)

Treatment length

Ask the trial team for details

Phase 1RecruitingPriority 4 · Lower priorityNCT03017820

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

This Phase 1 trial is comparing Biopsy Procedure, Biospecimen Collection, and other medications against other options for people whose a type of T-cell lymphoma called AITL has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 2 US locations.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

2 US sites · Arizona, Minnesota

Sponsor

Mayo Clinic

Treatment length

Ask the trial team for details

Phase 1RecruitingPriority 4 · Lower priorityNCT06508463

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

This Phase 1 trial is comparing Biopsy, Biospecimen Collection, and other medications against other options for people whose anaplastic large cell lymphoma (ALCL) has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 2 US locations.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

2 US sites · Arizona, Minnesota

Sponsor

Mayo Clinic

Treatment length

Ask the trial team for details

Early Phase 1RecruitingPriority 4 · Lower priorityNCT03719105

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

This Early Phase 1 trial is comparing different first-line treatment approaches for people newly diagnosed with anaplastic large cell lymphoma (ALCL). Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 6 US locations across multiple states.

Who it's for

  • Age 1 Year to 31 Years years
  • Newly diagnosed, not yet treated

Location

6 US sites · Alabama, California, Michigan +2

Sponsor

New York Medical College

Treatment length

Ask the trial team for details

Phase 1RecruitingPriority 4 · Lower priorityNCT06176690

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

This Phase 1 trial is testing C7R.CD30.CAR-EBVST cells for people whose ALK-negative ALCL has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. It is available at 2 US locations.

Who it's for

  • Age 12 Years to 75 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

2 US sites · Texas

Sponsor

Baylor College of Medicine

Treatment length

Ask the trial team for details

RecruitingPriority 4 · Lower priorityNCT03964480

Prospective Observational International Registry of Patients With Newly Diagnosed Peripheral T Cell Lymphoma.

This trial is evaluating a new treatment as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. It is available at 1 US location.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

1 US site · California

Sponsor

Associazione Angela Serra per la ricerca sul cancro

Treatment length

Ask the trial team for details

RecruitingPriority 4 · Lower priorityNCT07253129

Allo-HSCT Vs. Auto-HSCT for PTCL Patients With PR After First-line Systemic Therapy : A Prospective, Multicenter, Cohort Study-(T-START-PR)

This trial is evaluating Autologous Hematopoietic Stem Cell Transplantation and Allogenic stem cell transplant (ASCT) as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Treatment length

Ask the trial team for details

Phase 1Not yet recruitingPriority 4 · Lower priorityNCT06712173

Linperlisib Combined With EZH2 Inhibitor in Relapsed/Refractory Peripheral T-cell Lymphoma (PTCL)

This Phase 1 trial is testing linperlisib and SHR2554 for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Institute of Hematology & Blood Diseases Hospital, China

Treatment length

Ask the trial team for details

Phase 1RecruitingPriority 4 · Lower priorityNCT07164560

Exploratory Study of Umbilical Cord Blood-Derived CAR-NK Cell Therapy Targeting TRBC1/2 for Relapsed/Refractory T-Cell Lymphoma

This Phase 1 trial is testing Anti-TRBC1 CAR-T cells for people whose T-cell lymphoma has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Lymphoma came back or did not respond to prior treatment

Location

No US sites currently

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Treatment length

Ask the trial team for details

Phase 1RecruitingPriority 4 · Lower priorityNCT07001384

A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)

This Phase 1 trial is testing Alectinib and Duvelisib for people whose anaplastic large cell lymphoma (ALCL) has come back or has not responded to previous treatment. The study starts with lower doses to find the safest effective dose before testing in more people. It is available at 7 US locations across multiple states.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

7 US sites · New Jersey, New York

Sponsor

Memorial Sloan Kettering Cancer Center

Treatment length

Ask the trial team for details

Not yet recruitingPriority 4 · Lower priorityNCT07657572

A Multi-center, Prospective, Registry Study to Analyze the Clinical Characteristics and Prognosis of Different Molecular Subtypes of Peripheral T-cell Lymphoma.

This trial is studying a new treatment for people with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • See full trial listing for complete eligibility

Location

No US sites currently

Sponsor

Ruijin Hospital

Treatment length

Ask the trial team for details

NARecruitingPriority 4 · Lower priorityNCT07072221

Bendamustine Combined With Chidamide and Lenalidomide for Relapsed and Refractory PTCL Patients

This NA trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

The First Affiliated Hospital of Soochow University

Treatment length

Ask the trial team for details

NARecruitingPriority 4 · Lower priorityNCT07074457

Chidamide Combined With Brentuximab Vedotin Regimen for CD30+ PTCL Patients

This NA trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

The First Affiliated Hospital of Soochow University

Treatment length

Ask the trial team for details

RecruitingPriority 4 · Lower priorityNCT07270861

Real-world Outcomes of Peripheral T-cell Lymphoma: A Multicenter Retrospective and Prospective Cohort Study

This trial is evaluating Observational as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Fudan University

Treatment length

Ask the trial team for details

RecruitingPriority 4 · Lower priorityNCT07353840

T Cell Lymphoma -Stratified Therapy After Response to First-line Treatment-CR

This trial is evaluating Autologous Hematopoietic Stem Cell Transplantation and Observation as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Treatment length

Ask the trial team for details

Phase 1RecruitingPriority 4 · Lower priorityNCT05544968

Anti-CD30 biAb-AATC in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies

This Phase 1 trial is comparing anti-CD30 Bispecific Antibody-armed anti-CD3-Activated Autologous T-cells (CD30 biAb-AATC) and GM-CSF against other options for people whose anaplastic large cell lymphoma (ALCL) has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 1 US location.

Who it's for

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment

Location

1 US site · Wisconsin

Sponsor

Medical College of Wisconsin

Treatment length

Ask the trial team for details

RecruitingPriority 4 · Lower priorityNCT07470996

T Cell Lymphoma -Stratified Therapy After Response to First-line Treatment-NR

This trial is evaluating Allogenic stem cell transplant (ASCT) and Salvage Therapy as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Treatment length

Ask the trial team for details

RecruitingPriority 4 · Lower priorityNCT04220970

Breast Implant-associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Registry

This trial is studying BIA-ALCL for people with anaplastic large cell lymphoma (ALCL). The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • See full trial listing for complete eligibility

Location

No US sites currently

Sponsor

The Lymphoma Academic Research Organisation

Treatment length

Ask the trial team for details

Early Phase 1RecruitingPriority 4 · Lower priorityNCT07598578

An Open-label, Single-arm, Multicenter Phase II Clinical Study of Azacitidine, Chidamide Combined With PD-1 Monoclonal Antibody in the Treatment of Refractory/Relapsed Peripheral T-cell Lymphoma.

This Early Phase 1 trial is evaluating Azacitidine (AZA) as a treatment for people newly diagnosed with T-cell lymphoma. The study starts with lower doses to find the safest effective dose before testing in more people. This trial does not currently list US sites.

Who it's for

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Second Affiliated Hospital of Soochow University

Treatment length

Ask the trial team for details

Not yet recruitingPriority 4 · Lower priorityNCT07467317

BV-CHP Real-life and Biological Evidences in Patients With sALCL

This trial is evaluating a new treatment as a treatment for people newly diagnosed with anaplastic large cell lymphoma (ALCL). The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who it's for

  • Age 18 Years or older
  • Newly diagnosed, not yet treated

Location

No US sites currently

Sponsor

Fondazione Italiana Linfomi - ETS

Treatment length

Ask the trial team for details

Other T-cell lymphoma subtypes