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Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07535762

Aclarubicin Plus Cyclophosphamide, Vincristine, and Prednisone (CAOP) in Patients With Previously Untreated Peripheral T-Cell Lymphoma

ClinicalTrials.gov

Plain-language summary

This Phase 2 trial is evaluating Aclarubicin, Cyclophosphamide, and other medications as a treatment for people newly diagnosed with a type of T-cell lymphoma called AITL. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who can join (key eligibility)

  • Age 65 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Aclarubicin (DRUG): 20mg/m\^2/D, D1-4, QD, ivgtt | Cyclophosphamide (DRUG): 750 mg/m\^2, D1, ivgtt | Vincristine (DRUG): 1.4 mg/m\^2, D1 (maximum 2mg/d), IV | Prednisone (DRUG): 60 mg/m\^2, D1-5 (maximum 100mg/d), Po

Drugs / treatments
Aclarubicin, Cyclophosphamide, Vincristine, Prednisone
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 2
Status
Not yet recruiting
Design
Non-randomized, open-label
Enrollment target
36 patients
Primary endpoint
Complete remission rate (CR)
Ages
65 Years to —
Start date
2026-03-30
Est. completion
2028-12-30

Locations

0 US sites · 2 total

No US sites currently listed.

Contact

Sponsor
Shanghai Jiao Tong University School of Medicine (OTHER)
Contact
Jiong Hu | hj10709@rjh.com.cn | 86-13764313546

Tags

AITL/TFHALCLPTCL-NOSMaintenanceNewly diagnosed
TrialCompass — Clinical Trial Summary

Aclarubicin Plus Cyclophosphamide, Vincristine, and Prednisone (CAOP) in Patients With Previously Untreated Peripheral T-Cell Lymphoma

NCT07535762

Phase: Phase 2 | Status: Not yet recruiting | Priority: Medium

Plain-language summary

This Phase 2 trial is evaluating Aclarubicin, Cyclophosphamide, and other medications as a treatment for people newly diagnosed with a type of T-cell lymphoma called AITL. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who can join

  • Age 65 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

What's being tested

Aclarubicin (DRUG): 20mg/m\^2/D, D1-4, QD, ivgtt | Cyclophosphamide (DRUG): 750 mg/m\^2, D1, ivgtt | Vincristine (DRUG): 1.4 mg/m\^2, D1 (maximum 2mg/d), IV | Prednisone (DRUG): 60 mg/m\^2, D1-5 (maximum 100mg/d), Po

Drugs / treatments: Aclarubicin, Cyclophosphamide, Vincristine, Prednisone

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 36 patients

Primary endpoint: Complete remission rate (CR)

Ages: 65 Years to —

Start date: 2026-03-30 | Est. completion: 2028-12-30

Locations

0 US sites · 2 total

Contact

Jiong Hu | hj10709@rjh.com.cn | 86-13764313546

Sponsor: Shanghai Jiao Tong University School of Medicine (OTHER)

Tags

AITL/TFH · ALCL · PTCL-NOS · Maintenance · Newly diagnosed

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT07535762

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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