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Phase 2RecruitingPriority 2 · High priorityNCT07293403

Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas

ClinicalTrials.gov

Plain-language summary

This Phase 2 trial is evaluating Biospecimen Collection, Bone Marrow Aspiration, and other medications as a treatment for people newly diagnosed with a type of T-cell lymphoma called AITL. The study measures how well this treatment works and monitors for side effects. It is available at 1 US location.

Who can join (key eligibility)

  • Age 18 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)
  • May require specific number of prior treatments

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Biospecimen Collection (PROCEDURE): Undergo blood sample collection | Bone Marrow Aspiration (PROCEDURE): Undergo bone marrow aspiration | Bone Marrow Biopsy (PROCEDURE): Undergo bone marrow biopsy | Computed Tomography (PROCEDURE): Undergo CT scan | Duvelisib (DRUG): Given PO | Positron Emission Tomography (PROCEDURE): Undergo PET scan | Survey Administration (OTHER): Ancillary studies

Drugs / treatments
Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Duvelisib, Positron Emission Tomography, Survey Administration
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 2
Status
Recruiting
Design
Non-randomized, open-label
Enrollment target
25 patients
Primary endpoint
Progression free survival
Ages
18 Years to —
Start date
2026-06-07
Est. completion
2027-11-23

Locations

1 US sites · 1 total

California

Contact

Sponsor
City of Hope Medical Center (OTHER)
Contact
—

Tags

AITL/TFHPTCL-NOSMaintenanceNewly diagnosed
TrialCompass — Clinical Trial Summary

Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas

NCT07293403

Phase: Phase 2 | Status: Recruiting | Priority: High

Plain-language summary

This Phase 2 trial is evaluating Biospecimen Collection, Bone Marrow Aspiration, and other medications as a treatment for people newly diagnosed with a type of T-cell lymphoma called AITL. The study measures how well this treatment works and monitors for side effects. It is available at 1 US location.

Who can join

  • Age 18 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)
  • May require specific number of prior treatments

What's being tested

Biospecimen Collection (PROCEDURE): Undergo blood sample collection | Bone Marrow Aspiration (PROCEDURE): Undergo bone marrow aspiration | Bone Marrow Biopsy (PROCEDURE): Undergo bone marrow biopsy | Computed Tomography (PROCEDURE): Undergo CT scan | Duvelisib (DRUG): Given PO | Positron Emission Tomography (PROCEDURE): Undergo PET scan | Survey Administration (OTHER): Ancillary studies

Drugs / treatments: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Duvelisib, Positron Emission Tomography, Survey Administration

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 25 patients

Primary endpoint: Progression free survival

Ages: 18 Years to —

Start date: 2026-06-07 | Est. completion: 2027-11-23

Locations

1 US sites · 1 total

California

Contact

—

Sponsor: City of Hope Medical Center (OTHER)

Tags

AITL/TFH · PTCL-NOS · Maintenance · Newly diagnosed

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT07293403

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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