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Phase 1RecruitingPriority 4 · Lower priorityNCT06712810

Q702 for the Treatment of Patients With Hematologic Malignancies

ClinicalTrials.gov

Plain-language summary

This Phase 1 trial is evaluating Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, and other medications as a treatment for people newly diagnosed with cutaneous T-cell lymphoma (skin lymphoma). The study starts with lower doses to find the safest effective dose before testing in more people. It is available at 2 US locations.

Who can join (key eligibility)

  • Age 18 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)
  • May require specific number of prior treatments

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Axl/Mer/CSF1R Inhibitor Q702 (DRUG): Given PO | Biospecimen Collection (PROCEDURE): Undergo blood and urine sample collection | Bone Marrow Aspiration (PROCEDURE): Undergo bone marrow biopsy and aspiration | Bone Marrow Biopsy (PROCEDURE): Undergo bone marrow biopsy and aspiration | Computed Tomography (PROCEDURE): Undergo CT scan | Magnetic Resonance Imaging (PROCEDURE): Undergo MRI | Positron Emission Tomography (PROCEDURE): Undergo PET scan | Survey Administration (OTHER): Ancillary study

Drugs / treatments
Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography, Survey Administration
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 1
Status
Recruiting
Design
Non-randomized, open-label
Enrollment target
46 patients
Primary endpoint
Incidence of dose limiting toxicity; Overall response rate
Ages
18 Years to —
Start date
2025-08-27
Est. completion
2030-09-15

Locations

2 US sites · 2 total

ArizonaMinnesota

Contact

Sponsor
Mayo Clinic (OTHER)
Contact
Clinical Trials Referral Office | mayocliniccancerstudies@mayo.edu | 855-776-0015

Tags

CTCLPTCL-NOSNewly diagnosedRelapsed/Refractory
TrialCompass — Clinical Trial Summary

Q702 for the Treatment of Patients With Hematologic Malignancies

NCT06712810

Phase: Phase 1 | Status: Recruiting | Priority: Lower

Plain-language summary

This Phase 1 trial is evaluating Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, and other medications as a treatment for people newly diagnosed with cutaneous T-cell lymphoma (skin lymphoma). The study starts with lower doses to find the safest effective dose before testing in more people. It is available at 2 US locations.

Who can join

  • Age 18 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)
  • May require specific number of prior treatments

What's being tested

Axl/Mer/CSF1R Inhibitor Q702 (DRUG): Given PO | Biospecimen Collection (PROCEDURE): Undergo blood and urine sample collection | Bone Marrow Aspiration (PROCEDURE): Undergo bone marrow biopsy and aspiration | Bone Marrow Biopsy (PROCEDURE): Undergo bone marrow biopsy and aspiration | Computed Tomography (PROCEDURE): Undergo CT scan | Magnetic Resonance Imaging (PROCEDURE): Undergo MRI | Positron Emission Tomography (PROCEDURE): Undergo PET scan | Survey Administration (OTHER): Ancillary study

Drugs / treatments: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography, Survey Administration

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 46 patients

Primary endpoint: Incidence of dose limiting toxicity; Overall response rate

Ages: 18 Years to —

Start date: 2025-08-27 | Est. completion: 2030-09-15

Locations

2 US sites · 2 total

Arizona, Minnesota

Contact

Clinical Trials Referral Office | mayocliniccancerstudies@mayo.edu | 855-776-0015

Sponsor: Mayo Clinic (OTHER)

Tags

CTCL · PTCL-NOS · Newly diagnosed · Relapsed/Refractory

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT06712810

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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