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Phase 2RecruitingPriority 3 · Moderate priorityNCT05958719

Chidamide in Combination With Azacitidine, Liposomal Mitoxantrone, and Prednisone (CAMP Regimen) for the Treatment of Previously Untreated Nodal TFH Cell Lymphoma

ClinicalTrials.gov

Plain-language summary

This Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with a type of T-cell lymphoma called AITL. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join (key eligibility)

  • Age 18 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Chidamide (DRUG): chidamide 30mg biw, p.o, 21 days for a cycle. | Azacitidine (DRUG): 75mg/m2, continuous i.h. on day 1-7,21 days for a cycle. | liposomal mitoxantrone (DRUG): 12mg/m2, d1,21 days for a cycle. | prednisone (DRUG): 60mg/m2,d1-5,21 days for a cycle.

Drugs / treatments
Chidamide, Azacitidine, liposomal mitoxantrone, prednisone
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 2
Status
Recruiting
Design
Non-randomized, open-label
Enrollment target
37 patients
Primary endpoint
Objective Response Rate (ORR); Number of participants with treatment-related adverse events as assessed by CTCAE v5.0
Ages
18 Years to —
Start date
2023-03-02
Est. completion
2027-03-02

Locations

0 US sites · 1 total

No US sites currently listed.

Contact

Sponsor
Institute of Hematology & Blood Diseases Hospital, China (OTHER)
Contact
Dehui Zou, Dr. | zoudehui@ihcams.ac.cn | 86-022-23909282

Tags

AITL/TFHMaintenanceNewly diagnosed
TrialCompass — Clinical Trial Summary

Chidamide in Combination With Azacitidine, Liposomal Mitoxantrone, and Prednisone (CAMP Regimen) for the Treatment of Previously Untreated Nodal TFH Cell Lymphoma

NCT05958719

Phase: Phase 2 | Status: Recruiting | Priority: Medium

Plain-language summary

This Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with a type of T-cell lymphoma called AITL. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join

  • Age 18 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

What's being tested

Chidamide (DRUG): chidamide 30mg biw, p.o, 21 days for a cycle. | Azacitidine (DRUG): 75mg/m2, continuous i.h. on day 1-7,21 days for a cycle. | liposomal mitoxantrone (DRUG): 12mg/m2, d1,21 days for a cycle. | prednisone (DRUG): 60mg/m2,d1-5,21 days for a cycle.

Drugs / treatments: Chidamide, Azacitidine, liposomal mitoxantrone, prednisone

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 37 patients

Primary endpoint: Objective Response Rate (ORR); Number of participants with treatment-related adverse events as assessed by CTCAE v5.0

Ages: 18 Years to —

Start date: 2023-03-02 | Est. completion: 2027-03-02

Locations

0 US sites · 1 total

Contact

Dehui Zou, Dr. | zoudehui@ihcams.ac.cn | 86-022-23909282

Sponsor: Institute of Hematology & Blood Diseases Hospital, China (OTHER)

Tags

AITL/TFH · Maintenance · Newly diagnosed

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT05958719

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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