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Phase 2Not yet recruitingPriority 3 · Moderate priorityNCT07658924

Efficacy and Safety of Benvitimod Cream in Cutaneous T-Cell Lymphoma

ClinicalTrials.gov

Plain-language summary

This Phase 2 trial is studying Benvitimod Cream and Placebo cream for people with cutaneous T-cell lymphoma (skin lymphoma). Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join (key eligibility)

  • Age 18 Years or older
  • See full trial listing for complete eligibility

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Benvitimod Cream (DRUG): Applied topically to the randomly assigned target lesion (left or right side) once daily for up to 24 weeks. The application area will not exceed 2% of the body surface area. | Placebo cream (DRUG): A vehicle cream matching the appearance of benvitimod cream. Applied topically to the contralateral target lesion once daily for up to 24 weeks.

Drugs / treatments
Benvitimod Cream, Placebo cream
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 2
Status
Not yet recruiting
Design
Randomized, quadruple blind
Enrollment target
35 patients
Primary endpoint
Percentage change in modified Severity-Weighted Assessment Tool (mSWAT) score; Change in Pruritus Visual Analogue Scale (VAS) score
Ages
18 Years to —
Start date
2026-07-01
Est. completion
2027-10-01

Locations

0 US sites · 0 total

No US sites currently listed.

Contact

Sponsor
Peking University First Hospital (OTHER)
Contact
—

Tags

CTCLany
TrialCompass — Clinical Trial Summary

Efficacy and Safety of Benvitimod Cream in Cutaneous T-Cell Lymphoma

NCT07658924

Phase: Phase 2 | Status: Not yet recruiting | Priority: Medium

Plain-language summary

This Phase 2 trial is studying Benvitimod Cream and Placebo cream for people with cutaneous T-cell lymphoma (skin lymphoma). Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join

  • Age 18 Years or older
  • See full trial listing for complete eligibility

What's being tested

Benvitimod Cream (DRUG): Applied topically to the randomly assigned target lesion (left or right side) once daily for up to 24 weeks. The application area will not exceed 2% of the body surface area. | Placebo cream (DRUG): A vehicle cream matching the appearance of benvitimod cream. Applied topically to the contralateral target lesion once daily for up to 24 weeks.

Drugs / treatments: Benvitimod Cream, Placebo cream

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Randomized, quadruple blind

Enrollment target: 35 patients

Primary endpoint: Percentage change in modified Severity-Weighted Assessment Tool (mSWAT) score; Change in Pruritus Visual Analogue Scale (VAS) score

Ages: 18 Years to —

Start date: 2026-07-01 | Est. completion: 2027-10-01

Locations

0 US sites · 0 total

Contact

—

Sponsor: Peking University First Hospital (OTHER)

Tags

CTCL · any

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT07658924

Prepared using TrialCompass (trialcompass.com) on July 4, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

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Data last updated: June 2026

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