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Phase 2RecruitingPriority 3 · Moderate priorityNCT07628738

A Prospective Clinical Study on Reduced-intensity Radiotherapy for Stage I/II Low-risk Nasal-type NK/T-cell Lymphoma Achieving Complete Remission After Chemotherapy

ClinicalTrials.gov

Plain-language summary

This Phase 2 trial is studying reduced-intensity radiotherapy for people with NK/T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who can join (key eligibility)

  • Age 18 Years to 75 Years years
  • Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

reduced-intensity radiotherapy (RADIATION): The patients will receive radiotherapy. The target volume, determined based on the involvement of the primary tumor and sites of metastasis, will include the nasal cavity or Waldeyer's ring, with or without bilateral cervical lymphatic drainage areas. The prescribed dose is 45 Gy in 25 fractions, at 1.8 Gy per fraction per day, five days per week, to be completed within five weeks.

Drugs / treatments
reduced-intensity radiotherapy
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 2
Status
Recruiting
Design
Non-randomized, open-label
Enrollment target
39 patients
Primary endpoint
2-year local regional recurrence-free survival rate
Ages
18 Years to 75 Years
Start date
2026-07-01
Est. completion
2034-05-01

Locations

0 US sites · 1 total

No US sites currently listed.

Contact

Sponsor
Ruijin Hospital (OTHER)
Contact
Shu-Bei Wang, MD | wangshubei@163.com | +86-021-64370045

Tags

ENKTLany
TrialCompass — Clinical Trial Summary

A Prospective Clinical Study on Reduced-intensity Radiotherapy for Stage I/II Low-risk Nasal-type NK/T-cell Lymphoma Achieving Complete Remission After Chemotherapy

NCT07628738

Phase: Phase 2 | Status: Recruiting | Priority: Medium

Plain-language summary

This Phase 2 trial is studying reduced-intensity radiotherapy for people with NK/T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who can join

  • Age 18 Years to 75 Years years
  • Must be well enough for treatment (adequate performance status)

What's being tested

reduced-intensity radiotherapy (RADIATION): The patients will receive radiotherapy. The target volume, determined based on the involvement of the primary tumor and sites of metastasis, will include the nasal cavity or Waldeyer's ring, with or without bilateral cervical lymphatic drainage areas. The prescribed dose is 45 Gy in 25 fractions, at 1.8 Gy per fraction per day, five days per week, to be completed within five weeks.

Drugs / treatments: reduced-intensity radiotherapy

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 39 patients

Primary endpoint: 2-year local regional recurrence-free survival rate

Ages: 18 Years to 75 Years

Start date: 2026-07-01 | Est. completion: 2034-05-01

Locations

0 US sites · 1 total

Contact

Shu-Bei Wang, MD | wangshubei@163.com | +86-021-64370045

Sponsor: Ruijin Hospital (OTHER)

Tags

ENKTL · any

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT07628738

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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