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Phase 1RecruitingPriority 4 · Lower priorityNCT07047885

Ropeginterferon in Patients w/Cutaneous T-Cell Lymphoma (CTCL)

ClinicalTrials.gov

Plain-language summary

This Phase 1 trial is comparing Ropeginterferon alfa-2b against other options for people whose cutaneous T-cell lymphoma (skin lymphoma) has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 1 US location.

Who can join (key eligibility)

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment
  • May require specific number of prior treatments

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Ropeginterferon alfa-2b (DRUG): Will be administered via subcutaneous injection once every 2 weeks

Drugs / treatments
Ropeginterferon alfa-2b
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 1
Status
Recruiting
Design
Non-randomized, open-label
Enrollment target
38 patients
Primary endpoint
Dose Limiting Toxicity; Recommended Phase II Dose
Ages
18 Years to —
Start date
2025-08-27
Est. completion
2028-06

Locations

1 US sites · 1 total

Florida

Contact

Sponsor
H. Lee Moffitt Cancer Center and Research Institute (OTHER)
Contact
Richard Corona | Richard.Corona@moffitt.org | 813-745-3465

Tags

CTCLRelapsed/Refractory
TrialCompass — Clinical Trial Summary

Ropeginterferon in Patients w/Cutaneous T-Cell Lymphoma (CTCL)

NCT07047885

Phase: Phase 1 | Status: Recruiting | Priority: Lower

Plain-language summary

This Phase 1 trial is comparing Ropeginterferon alfa-2b against other options for people whose cutaneous T-cell lymphoma (skin lymphoma) has come back or has not responded to previous treatment. Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 1 US location.

Who can join

  • Age 18 Years or older
  • Lymphoma came back or did not respond to prior treatment
  • May require specific number of prior treatments

What's being tested

Ropeginterferon alfa-2b (DRUG): Will be administered via subcutaneous injection once every 2 weeks

Drugs / treatments: Ropeginterferon alfa-2b

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 38 patients

Primary endpoint: Dose Limiting Toxicity; Recommended Phase II Dose

Ages: 18 Years to —

Start date: 2025-08-27 | Est. completion: 2028-06

Locations

1 US sites · 1 total

Florida

Contact

Richard Corona | Richard.Corona@moffitt.org | 813-745-3465

Sponsor: H. Lee Moffitt Cancer Center and Research Institute (OTHER)

Tags

CTCL · Relapsed/Refractory

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT07047885

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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