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Phase 3RecruitingPriority 2 · High priorityNCT06122389

SHR2554 Clinical Study of Chidamide in the Treatment of T-cell Lymphoma

ClinicalTrials.gov

Plain-language summary

This Phase 3 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join (key eligibility)

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

SHR2554; Chidamide analog tablets (DRUG): SHR2554 + Chidamide analog tablets | SHR2554 analog tablets; Chidamide (DRUG): SHR2554 analog tablets + Chidamide

Drugs / treatments
SHR2554; Chidamide analog tablets, SHR2554 analog tablets; Chidamide
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 3
Status
Recruiting
Design
Randomized, quadruple blind
Enrollment target
130 patients
Primary endpoint
Progression Free Survival (PFS) assessed by IRC
Ages
18 Years to 70 Years
Start date
2024-02-05
Est. completion
2026-07

Locations

0 US sites · 1 total

No US sites currently listed.

Contact

Sponsor
Jiangsu HengRui Medicine Co., Ltd. (INDUSTRY)
Contact
Min Li | Min.li.ml150@hengrui.com | 0518-82342973

Tags

All T-cell lymphomasNewly diagnosedRelapsed/Refractory
TrialCompass — Clinical Trial Summary

SHR2554 Clinical Study of Chidamide in the Treatment of T-cell Lymphoma

NCT06122389

Phase: Phase 3 | Status: Recruiting | Priority: High

Plain-language summary

This Phase 3 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

What's being tested

SHR2554; Chidamide analog tablets (DRUG): SHR2554 + Chidamide analog tablets | SHR2554 analog tablets; Chidamide (DRUG): SHR2554 analog tablets + Chidamide

Drugs / treatments: SHR2554; Chidamide analog tablets, SHR2554 analog tablets; Chidamide

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Randomized, quadruple blind

Enrollment target: 130 patients

Primary endpoint: Progression Free Survival (PFS) assessed by IRC

Ages: 18 Years to 70 Years

Start date: 2024-02-05 | Est. completion: 2026-07

Locations

0 US sites · 1 total

Contact

Min Li | Min.li.ml150@hengrui.com | 0518-82342973

Sponsor: Jiangsu HengRui Medicine Co., Ltd. (INDUSTRY)

Tags

All T-cell lymphomas · Newly diagnosed · Relapsed/Refractory

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT06122389

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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