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Phase 2RecruitingPriority 3 · Moderate priorityNCT05963347

Go-CHOP as the Frontline Therapy for PTCL

ClinicalTrials.gov

Plain-language summary

This Phase 2 trial is evaluating Golidocitinib and CHOP Regimen as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who can join (key eligibility)

  • Age 18 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Golidocitinib (DRUG): Daily dose. Starting dose of golidocitinib is 75 mg QD. If tolerated, subsequent cohorts will test ascending doses of golidocitinib. | CHOP Regimen (DRUG): CHOP will be administered in a 21-day cycle for a maximum of 6 cycles.

Drugs / treatments
Golidocitinib, CHOP Regimen
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 2
Status
Recruiting
Design
Non-randomized, open-label
Enrollment target
45 patients
Primary endpoint
Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]
Ages
18 Years to —
Start date
2023-08-03
Est. completion
2026-07-31

Locations

0 US sites · 1 total

No US sites currently listed.

Contact

Sponsor
Henan Cancer Hospital (OTHER_GOV)
Contact
Keshu Zhou, Dr. | drzhouks77@163.com | +86 (0371) 65587513

Tags

All T-cell lymphomasNewly diagnosedRelapsed/Refractory
TrialCompass — Clinical Trial Summary

Go-CHOP as the Frontline Therapy for PTCL

NCT05963347

Phase: Phase 2 | Status: Recruiting | Priority: Medium

Plain-language summary

This Phase 2 trial is evaluating Golidocitinib and CHOP Regimen as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who can join

  • Age 18 Years or older
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

What's being tested

Golidocitinib (DRUG): Daily dose. Starting dose of golidocitinib is 75 mg QD. If tolerated, subsequent cohorts will test ascending doses of golidocitinib. | CHOP Regimen (DRUG): CHOP will be administered in a 21-day cycle for a maximum of 6 cycles.

Drugs / treatments: Golidocitinib, CHOP Regimen

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 45 patients

Primary endpoint: Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]

Ages: 18 Years to —

Start date: 2023-08-03 | Est. completion: 2026-07-31

Locations

0 US sites · 1 total

Contact

Keshu Zhou, Dr. | drzhouks77@163.com | +86 (0371) 65587513

Sponsor: Henan Cancer Hospital (OTHER_GOV)

Tags

All T-cell lymphomas · Newly diagnosed · Relapsed/Refractory

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT05963347

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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