Plain-language summary

This Phase 3 trial is studying Low-dose total-skin electron-beam therapy and Phototherapy for people with cutaneous T-cell lymphoma (skin lymphoma). Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join (key eligibility)

• Age 18 Years or older
• Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Low-dose total-skin electron-beam therapy (OTHER): Low-dose total skin electron beam therapy (12 Gy) will be delivered to the patient in 4 Gy/week, 1 Gy/day over 3 weeks by symmetrical electron beams of 6 MeV energy via a linac accelerator. | Phototherapy (OTHER): Phototherapy will be given 3 times a week during 2 months, then twice a week during one month, then once a week during one month, or until disease progression or unacceptable side effect, whatever comes first. Patients with plaques will receive PUVA therapy and patients with patches only will receive narrow-band UVB therapy.

Drugs / treatments

Low-dose total-skin electron-beam therapy, Phototherapy

Treatment length

Ask the trial team for details

Visit frequency

Ask the trial team for details