TrialCompass TCL
Find TrialsAI AssistantLetter GeneratorAbout
Back to results
Phase 2RecruitingPriority 3 · Moderate priorityNCT04922567

Efficacy and Safety of Lenalidomide Plus CHOP vs CHOP in Patients With Untreated Peripheral T-Cell Lymphoma

ClinicalTrials.gov

Plain-language summary

This Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join (key eligibility)

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Lenalidomide (DRUG): 25mg po on day 1-10 | Cyclophosphamide (DRUG): 750mg/m² iv on day1 | Doxorubicin (DRUG): 50mg/m² iv on day 1 | Vincristine (DRUG): 1.4mg/m² iv on day 1 | Prednisone (DRUG): 100mg po on day1-5

Drugs / treatments
Lenalidomide, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 2
Status
Recruiting
Design
Randomized, open-label
Enrollment target
289 patients
Primary endpoint
Objective Response rate
Ages
18 Years to 75 Years
Start date
2021-04-01
Est. completion
2026-12-31

Locations

0 US sites · 1 total

No US sites currently listed.

Contact

Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University (OTHER)
Contact
Wenbin Qian, Prof. | qianwb@zju.edu.cn | +86-13605801032

Tags

All T-cell lymphomasNewly diagnosed
TrialCompass — Clinical Trial Summary

Efficacy and Safety of Lenalidomide Plus CHOP vs CHOP in Patients With Untreated Peripheral T-Cell Lymphoma

NCT04922567

Phase: Phase 2 | Status: Recruiting | Priority: Medium

Plain-language summary

This Phase 2 trial is comparing different first-line treatment approaches for people newly diagnosed with T-cell lymphoma. Patients are randomly assigned to different treatment groups to see which approach works best. This trial does not currently list US sites.

Who can join

  • Age 18 Years to 75 Years years
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

What's being tested

Lenalidomide (DRUG): 25mg po on day 1-10 | Cyclophosphamide (DRUG): 750mg/m² iv on day1 | Doxorubicin (DRUG): 50mg/m² iv on day 1 | Vincristine (DRUG): 1.4mg/m² iv on day 1 | Prednisone (DRUG): 100mg po on day1-5

Drugs / treatments: Lenalidomide, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Randomized, open-label

Enrollment target: 289 patients

Primary endpoint: Objective Response rate

Ages: 18 Years to 75 Years

Start date: 2021-04-01 | Est. completion: 2026-12-31

Locations

0 US sites · 1 total

Contact

Wenbin Qian, Prof. | qianwb@zju.edu.cn | +86-13605801032

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University (OTHER)

Tags

All T-cell lymphomas · Newly diagnosed

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT04922567

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
TrialCompass

A free tool to help patients, caregivers, and clinicians find and understand clinical trials for T-cell lymphoma.

Explore

  • Find Trials
  • AI Assistant
  • Letter Generator
  • About
  • Share Your Feedback
  • Terms of Use
  • Privacy Policy

Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

Edit with