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NARecruitingPriority 4 · Lower priorityNCT04045470

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

ClinicalTrials.gov

Plain-language summary

This NA trial is studying Microdevices, Standard of care therapy, and other medications for people with cutaneous T-cell lymphoma (skin lymphoma). Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 1 US location.

Who can join (key eligibility)

  • Age 18 Years or older
  • Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

Microdevices (DEVICE): The microdevice was developed as a tool with the ultimate goal to help screen several existing and investigational drugs directly within a patient's tumor to identify what drugs are the most effective for treating a patient's cancer. | Standard of care therapy (OTHER): Participant to receive standard of care therapy as previously determined by participant's treating oncologist and/or dermatologist, which may include a skin-directed or systemic therapy | Standard of care systemic therapy (OTHER): Participant to receive standard of care therapy as previously determined by participant's treating oncologist and/or dermatologist, which must include a systemic therapy.

Drugs / treatments
Microdevices, Standard of care therapy, Standard of care systemic therapy
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
NA
Status
Recruiting
Design
Non-randomized, open-label
Enrollment target
20 patients
Primary endpoint
To Quantify The Number Of Microdevice-Related Failures Or Adverse Events As Assessed By CTCAE v4.0 After Microdevice Placement and Removal; To Retrieve The Device With Sufficient Tissue Of Sufficient Quality
Ages
18 Years to —
Start date
2019-12-11
Est. completion
2027-01-01

Locations

1 US sites · 1 total

Massachusetts

Contact

Sponsor
Dana-Farber Cancer Institute (OTHER)
Contact
Cecilia Larocca, MD | clarocca@partners.org | 617-632-6571

Tags

CTCLany
TrialCompass — Clinical Trial Summary

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

NCT04045470

Phase: NA | Status: Recruiting | Priority: Lower

Plain-language summary

This NA trial is studying Microdevices, Standard of care therapy, and other medications for people with cutaneous T-cell lymphoma (skin lymphoma). Patients are randomly assigned to different treatment groups to see which approach works best. It is available at 1 US location.

Who can join

  • Age 18 Years or older
  • Must be well enough for treatment (adequate performance status)

What's being tested

Microdevices (DEVICE): The microdevice was developed as a tool with the ultimate goal to help screen several existing and investigational drugs directly within a patient's tumor to identify what drugs are the most effective for treating a patient's cancer. | Standard of care therapy (OTHER): Participant to receive standard of care therapy as previously determined by participant's treating oncologist and/or dermatologist, which may include a skin-directed or systemic therapy | Standard of care systemic therapy (OTHER): Participant to receive standard of care therapy as previously determined by participant's treating oncologist and/or dermatologist, which must include a systemic therapy.

Drugs / treatments: Microdevices, Standard of care therapy, Standard of care systemic therapy

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 20 patients

Primary endpoint: To Quantify The Number Of Microdevice-Related Failures Or Adverse Events As Assessed By CTCAE v4.0 After Microdevice Placement and Removal; To Retrieve The Device With Sufficient Tissue Of Sufficient Quality

Ages: 18 Years to —

Start date: 2019-12-11 | Est. completion: 2027-01-01

Locations

1 US sites · 1 total

Massachusetts

Contact

Cecilia Larocca, MD | clarocca@partners.org | 617-632-6571

Sponsor: Dana-Farber Cancer Institute (OTHER)

Tags

CTCL · any

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT04045470

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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