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Phase 2RecruitingPriority 3 · Moderate priorityNCT06433362

CMOEP in the Treatment of Untreated Peripheral T-cell Lymphoma

ClinicalTrials.gov

Plain-language summary

This Phase 2 trial is evaluating CMOEP as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who can join (key eligibility)

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

Final eligibility is determined by the trial team. This list is a starting point only.

What's being tested

CMOEP (DRUG): Drug: Mitoxantrone hydrochloride liposome Mitoxantrone hydrochloride liposome (18 mg/m\^2) on day 1, every 3 weeks; Drug: Cyclophosphamide Cyclophosphamide(750 mg/m\^2) on day 1,every 3 weeks; Drug: Vincristine Vincristine (1.4mg/ m2,Max dose 2mg) will be administered by an intravenous injection on day 1(Or at the discretion of the investigator, use other vinblastine drugs with the same mechanism, such as vindesine 3 mg/m2, the maximum dose of 4mg),every 3 weeks; Drug: Etoposide Etoposide (60 mg/ m2) will be administered by an intravenous infusion on day 1-3,every 3 weeks;

Drugs / treatments
CMOEP
Treatment length
Ask the trial team for details
Visit frequency
Ask the trial team for details

At a glance

Phase
Phase 2
Status
Recruiting
Design
Non-randomized, open-label
Enrollment target
115 patients
Primary endpoint
Complete Response Rate (CRR)
Ages
18 Years to 70 Years
Start date
2024-06-01
Est. completion
2026-06-30

Locations

0 US sites · 1 total

No US sites currently listed.

Contact

Sponsor
Tianjin Medical University Cancer Institute and Hospital (OTHER)
Contact
Jingwei Yu | jingweiyu@pku.org.cn | 86-15022015208

Tags

All T-cell lymphomasNewly diagnosed
TrialCompass — Clinical Trial Summary

CMOEP in the Treatment of Untreated Peripheral T-cell Lymphoma

NCT06433362

Phase: Phase 2 | Status: Recruiting | Priority: Medium

Plain-language summary

This Phase 2 trial is evaluating CMOEP as a treatment for people newly diagnosed with T-cell lymphoma. The study measures how well this treatment works and monitors for side effects. This trial does not currently list US sites.

Who can join

  • Age 18 Years to 70 Years years
  • Newly diagnosed, not yet treated
  • Must be well enough for treatment (adequate performance status)

What's being tested

CMOEP (DRUG): Drug: Mitoxantrone hydrochloride liposome Mitoxantrone hydrochloride liposome (18 mg/m\^2) on day 1, every 3 weeks; Drug: Cyclophosphamide Cyclophosphamide(750 mg/m\^2) on day 1,every 3 weeks; Drug: Vincristine Vincristine (1.4mg/ m2,Max dose 2mg) will be administered by an intravenous injection on day 1(Or at the discretion of the investigator, use other vinblastine drugs with the same mechanism, such as vindesine 3 mg/m2, the maximum dose of 4mg),every 3 weeks; Drug: Etoposide Etoposide (60 mg/ m2) will be administered by an intravenous infusion on day 1-3,every 3 weeks;

Drugs / treatments: CMOEP

Treatment length: Ask the trial team for details

Visit frequency: Ask the trial team for details

Trial design

Non-randomized, open-label

Enrollment target: 115 patients

Primary endpoint: Complete Response Rate (CRR)

Ages: 18 Years to 70 Years

Start date: 2024-06-01 | Est. completion: 2026-06-30

Locations

0 US sites · 1 total

Contact

Jingwei Yu | jingweiyu@pku.org.cn | 86-15022015208

Sponsor: Tianjin Medical University Cancer Institute and Hospital (OTHER)

Tags

All T-cell lymphomas · Newly diagnosed

View on ClinicalTrials.gov

https://clinicaltrials.gov/study/NCT06433362

Prepared using TrialCompass (trialcompass.com) on June 19, 2026. For informational purposes only. Always discuss with your healthcare team.
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Data sourced from ClinicalTrials.gov.

For informational purposes only. Not medical advice — always consult your healthcare team.

Built with care for the rare cancer community.

Data last updated: June 2026

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